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Monday, July 5, 2010
Sunday, July 13, 2008
Retinal transplant boosts vision
An experimental transplant of cells into the eyes of patients with failing sight improved vision in most of them, US researchers say.
The retinal cells, taken from aborted foetuses, were implanted into 10 people with retinitis pigmentosa and age-related macular degeneration.
The American Journal of Ophthalmology study found seven had better - although still seriously impaired - vision.
A UK expert said successful retinal transplant is science's "holy grail".
Retinitis pigmentosa and age-related macular degeneration (AMD) are the most common causes of blindness in old age, and involve the gradual and normally irreversible destruction of the cells on the eye's retina which receive light.
The technique used by the team at the University of Louisville, Kentucky, saw them implant the foetal retinal cells alongside cells which have the job of nourishing them, with the hope that the new cells would join forces with the existing retinal cells to improve overall vision.
Dr Norman Radtke, who led the project, said that sight tests showed no change in three of the 10 patients, but slight improvements in the rest.
In one case, this improvement was still present six years after the operation, even though the patient's other eye had continued to deteriorate.
However, the improvements were only modest, and eyesight was well short of normal vision.
Dr Radtke said: "What we have learned will help us to refine this method and obtain further evidence that retinal transplants may be a viable therapy for retinal degenerative disease."
Ethical problems
Professor Pete Coffey, from the University College London Institute of Ophthalmology, said that the results did not suggest a major improvement in vision.
"I can't say that this is a success, except in the suggestion that the cells did not provoke an immune reaction in the recipient."
He said that no-one had yet managed a completely-successful transplant, which he described as the "holy grail" in the field.
He said that the use of foetal cells was also impractical, both for ethical reasons, and for sheer lack of supply.
"Unlike a stem cell line, every time you need new cells you need another foetus."
The retinal cells, taken from aborted foetuses, were implanted into 10 people with retinitis pigmentosa and age-related macular degeneration.
The American Journal of Ophthalmology study found seven had better - although still seriously impaired - vision.
A UK expert said successful retinal transplant is science's "holy grail".
Retinitis pigmentosa and age-related macular degeneration (AMD) are the most common causes of blindness in old age, and involve the gradual and normally irreversible destruction of the cells on the eye's retina which receive light.
The technique used by the team at the University of Louisville, Kentucky, saw them implant the foetal retinal cells alongside cells which have the job of nourishing them, with the hope that the new cells would join forces with the existing retinal cells to improve overall vision.
Dr Norman Radtke, who led the project, said that sight tests showed no change in three of the 10 patients, but slight improvements in the rest.
In one case, this improvement was still present six years after the operation, even though the patient's other eye had continued to deteriorate.
However, the improvements were only modest, and eyesight was well short of normal vision.
Dr Radtke said: "What we have learned will help us to refine this method and obtain further evidence that retinal transplants may be a viable therapy for retinal degenerative disease."
Ethical problems
Professor Pete Coffey, from the University College London Institute of Ophthalmology, said that the results did not suggest a major improvement in vision.
"I can't say that this is a success, except in the suggestion that the cells did not provoke an immune reaction in the recipient."
He said that no-one had yet managed a completely-successful transplant, which he described as the "holy grail" in the field.
He said that the use of foetal cells was also impractical, both for ethical reasons, and for sheer lack of supply.
"Unlike a stem cell line, every time you need new cells you need another foetus."
Pollution board slaps notices on hospitals, nursing homes
The West Bengal Pollution Control Board (WBPCB) has issued warning notices to some nursing homes and hospitals for not adhering to bio-waste management norms.
Bio-Medical Waste (Management and Handling) Rules, 1998
as amended in 2000 by the Centre mandates proper segregation, treatment, transport and disposal of the infectious bio-medical wastes for the safeguard of public health.
The onus of ensuring proper treatment of such wastes lies squarely with the hospitals and nursing homes. The municipalities and private bodies are only supposed to pick up and transport duly treated bio-medical wastes for disposal at the municipal dumping site.
According to Chief Scientist of the WBPCB Dipak Chakraborty, while two private nursing homes have been given ‘closure notice’ with a one-month time period, the others have been heavily fined for not segregating the bio-medical waste in an eco-friendly manner.
At an interactive session, which was organised by Concern for Calcutta, a non-governmental organisation, alongwith WBPCB and Kolkata Municipal Corporation (KMC), experts stressed on the need for better and stricter monitoring.
Apart from the two hospitals, notices have also been issued to a few other medical establishments. They were also fined Rs 50,000 for spreading pollution with bio-medical wastes.
While the nursing homes are located in the Ekbalpore and Kidderpore area, the hospital is located in Ultadanga.
Chakraborty said: “We had issued notices to several hospitals and nursing homes after finding that they were not segregating bio-medical wastes properly before disposal. A nursing home in Salt Lake has been issued a closure notice within a month.”
Though the nursing homes claimed they segregate and mutate the waste following the safety measures before disposing them off through a private agency, WBPCB’s inspection revealed otherwise.
Bio-Medical Waste (Management and Handling) Rules, 1998
as amended in 2000 by the Centre mandates proper segregation, treatment, transport and disposal of the infectious bio-medical wastes for the safeguard of public health.
The onus of ensuring proper treatment of such wastes lies squarely with the hospitals and nursing homes. The municipalities and private bodies are only supposed to pick up and transport duly treated bio-medical wastes for disposal at the municipal dumping site.
According to Chief Scientist of the WBPCB Dipak Chakraborty, while two private nursing homes have been given ‘closure notice’ with a one-month time period, the others have been heavily fined for not segregating the bio-medical waste in an eco-friendly manner.
At an interactive session, which was organised by Concern for Calcutta, a non-governmental organisation, alongwith WBPCB and Kolkata Municipal Corporation (KMC), experts stressed on the need for better and stricter monitoring.
Apart from the two hospitals, notices have also been issued to a few other medical establishments. They were also fined Rs 50,000 for spreading pollution with bio-medical wastes.
While the nursing homes are located in the Ekbalpore and Kidderpore area, the hospital is located in Ultadanga.
Chakraborty said: “We had issued notices to several hospitals and nursing homes after finding that they were not segregating bio-medical wastes properly before disposal. A nursing home in Salt Lake has been issued a closure notice within a month.”
Though the nursing homes claimed they segregate and mutate the waste following the safety measures before disposing them off through a private agency, WBPCB’s inspection revealed otherwise.
Obese And Ignorant About It: Certainly Not A Bliss
‘Ignorance is bliss’, goes the age old adage. However, this axiom might not hold water for a quarter of the British population who are unaware of the fact that they are obese. A study conducted by the British Medical Journal revealed that only seventy five percent of the obese admitted that they were obese.
While it is common knowledge in medical fraternity that overweight people run a greater risk of developing diseases like diabetes, heart disease and cancerdefine, Britain finds itself in a situation where more than half of the country is overweight or obese, but only three –fourth of such people are conscious of it.
What is more discouraging is that the proportion of this ‘unaware’ segment has increased since 1999. Eight years ago eighty one cent of those who were obese and overweight identified themselves in the correct category as against seventy five percent in 2007.
The study used Body mass indexdefine (BMI) as a tool to define people as obese or not. BMI is defined as the individual's body weight divided by the square of their height. This formula is also universally used in medicine produce a unit of measure of kg/m2.
As a thumb rule, people with less than 16.5 BMI are considered severely underweight, with a BMI of between 20 and 25 are considered to have a healthy weight, while a BMI of between 25 and 30 is overweight. A BMI from 35 to 40 indicates clinically obese people and a BMI of above 40 indicates morbidly Obese.
Professor Jane Wardle, who led the study, observed, "Increased attention to the health risks of excess weight might have left individuals more reluctant to identify themselves with labels such as 'overweight' or 'obese'.
She further observed, "Certainly, there is evidence that some overweight individuals resist identifying with terminology that they perceive as stigmatizing, preferring to adopt euphemistic identifiers for overweight such as 'chubby' or 'big boned'."
An alarming trend seen is that fat people are increasing by the day, thus making it trickier for those who are overweight to identify their problem. In the present day Britain, people have become accustomed to seeing more of the population carrying extra pounds.
While it is common knowledge in medical fraternity that overweight people run a greater risk of developing diseases like diabetes, heart disease and cancerdefine, Britain finds itself in a situation where more than half of the country is overweight or obese, but only three –fourth of such people are conscious of it.
What is more discouraging is that the proportion of this ‘unaware’ segment has increased since 1999. Eight years ago eighty one cent of those who were obese and overweight identified themselves in the correct category as against seventy five percent in 2007.
The study used Body mass indexdefine (BMI) as a tool to define people as obese or not. BMI is defined as the individual's body weight divided by the square of their height. This formula is also universally used in medicine produce a unit of measure of kg/m2.
As a thumb rule, people with less than 16.5 BMI are considered severely underweight, with a BMI of between 20 and 25 are considered to have a healthy weight, while a BMI of between 25 and 30 is overweight. A BMI from 35 to 40 indicates clinically obese people and a BMI of above 40 indicates morbidly Obese.
Professor Jane Wardle, who led the study, observed, "Increased attention to the health risks of excess weight might have left individuals more reluctant to identify themselves with labels such as 'overweight' or 'obese'.
She further observed, "Certainly, there is evidence that some overweight individuals resist identifying with terminology that they perceive as stigmatizing, preferring to adopt euphemistic identifiers for overweight such as 'chubby' or 'big boned'."
An alarming trend seen is that fat people are increasing by the day, thus making it trickier for those who are overweight to identify their problem. In the present day Britain, people have become accustomed to seeing more of the population carrying extra pounds.
Hong Kong pickpockets open show at Osian's
Producer-director Johnny To, whose film about a gang of pickpocketers opened the 10th Osian's- Cinefan Film Festival here is optimistic that the recession faced by the movie industry worldwide will soon be over and filmmakers would create more films catering to the changing tastes of audiences.
In the capital for the ongoing festival that began on July 10, To's 'Sparrow' departs from his usual style of gangster sagas to present a comic breezy film about a gang of four brothers all pickpockets.
"After 10 years of gangster, police and action movies the 'Sparrow' is a leap for me in a way," To says.
Explaining the choice of the film, he says, "Sparrow means a pickpocket in Hong Kong. I chose sparrow as the main subject of the film as the old city of Hong Kong is disappearing making way for this old profession of pickpockets is also slowly disappearing." "Hong Kong is mainly a city of immigrants during war and afterwards who come to the city before they move on. Today the old buildings of the city are torn down to make way for newer property development ventures that have a lot of money in it. Through Sparrow you can see the old Hong Kong," said the international director using a translator.
"In 10 years Hong Kong cinema has witnessed a lot of change. Previously there were very local movies especially comedies with formulae that were repeated endlessly. Today the films are more experimental, more personal and of course there are the traditional kung fu style of movies too," says To. PTI
In the capital for the ongoing festival that began on July 10, To's 'Sparrow' departs from his usual style of gangster sagas to present a comic breezy film about a gang of four brothers all pickpockets.
"After 10 years of gangster, police and action movies the 'Sparrow' is a leap for me in a way," To says.
Explaining the choice of the film, he says, "Sparrow means a pickpocket in Hong Kong. I chose sparrow as the main subject of the film as the old city of Hong Kong is disappearing making way for this old profession of pickpockets is also slowly disappearing." "Hong Kong is mainly a city of immigrants during war and afterwards who come to the city before they move on. Today the old buildings of the city are torn down to make way for newer property development ventures that have a lot of money in it. Through Sparrow you can see the old Hong Kong," said the international director using a translator.
"In 10 years Hong Kong cinema has witnessed a lot of change. Previously there were very local movies especially comedies with formulae that were repeated endlessly. Today the films are more experimental, more personal and of course there are the traditional kung fu style of movies too," says To. PTI
Friday, July 11, 2008
Terror threat to Games: China shuts mosques
Chinese authorities have replaced top police and security officials in the Muslim dominated Xinjiang province, which is the hotbed of separatism and political violence. They have also closed down 41 "illegal" places of worship.
These places of worship were used as training ground for conducting a "holy war", Chen Zhuangwei Chen, the police chief of Urumqi, capital of the Xinjiang province, said. Xinjiang, which borders central Asia and Pakistan, has been the scene of a pro-independence movement by a section of the eight million Uighurs living there for a long time.
The authorities also announced they have detained 82 "suspected terrorists" in the past six months in view of fears that they might disrupt the Olympic Games. They belong to five groups that "allegedly plotted sabotage against the Beijing Olympics", the official Xinhua news agency quoted the police chief in Urumqi, Xinjiang's capital, as saying.
The government has annouced the replacement of army and security officials in the ranks of three deputy core commanders, political commissars and the head of the Communist Party organisation department in the army. The replacement suggests that the central government has been unhappy about the inability of local officials to put down the surging separatist movement in the province.
The new head of the organisation department is Liu Xiang Song, the government announced. One of the three new core commanders is Hanabati Sabukhaya, an officer from the Kazak race. Xinjiang borders Kazakisthan and several other countries including Pakistan and Russia. "From now, all police officers must act urgently, get involved once more in Olympic security, to make sure large and small incidents alike do not happen," Chen was quoted by official media as saying.
These places of worship were used as training ground for conducting a "holy war", Chen Zhuangwei Chen, the police chief of Urumqi, capital of the Xinjiang province, said. Xinjiang, which borders central Asia and Pakistan, has been the scene of a pro-independence movement by a section of the eight million Uighurs living there for a long time.
The authorities also announced they have detained 82 "suspected terrorists" in the past six months in view of fears that they might disrupt the Olympic Games. They belong to five groups that "allegedly plotted sabotage against the Beijing Olympics", the official Xinhua news agency quoted the police chief in Urumqi, Xinjiang's capital, as saying.
The government has annouced the replacement of army and security officials in the ranks of three deputy core commanders, political commissars and the head of the Communist Party organisation department in the army. The replacement suggests that the central government has been unhappy about the inability of local officials to put down the surging separatist movement in the province.
The new head of the organisation department is Liu Xiang Song, the government announced. One of the three new core commanders is Hanabati Sabukhaya, an officer from the Kazak race. Xinjiang borders Kazakisthan and several other countries including Pakistan and Russia. "From now, all police officers must act urgently, get involved once more in Olympic security, to make sure large and small incidents alike do not happen," Chen was quoted by official media as saying.
Indian chef creates 'world's hottest curry'
An Indian chef has created the "hottest curry in the world" dubbed Bollywood Burner - a lamb-based dish which comes with a health warning as it contains a chilli that is 100 times hotter than a regular one.
The 'brain storming' dish has been created by executive chef Vivek Singh of London's Chinnamon Club restaurant, for a contest that marks the launch of Virgin Media's Bollywood Movies on Demand service.
The dish containing the Dorset Naga, a chilli that is 100 times hotter than a regular jalapeno as well as lamb and other peppers, is so hot that it comes with a health warning. Diners are required to sign a disclaimer saying they are aware of the nature and risks involved in tasting the curry before eating it.
Toby Steele, 19, a student from Brighton, was the first to taste the dish at the restaurant on Great Smith Street in Westminster.
"I'm usually a korma man and I suspect this is the hottest thing I've ever tasted. It was nice actually, you could really taste the spices. The initial taste wasn't that hot but a couple of minutes later, I felt a bit floaty and light-headed," he said. Vivek Singh said that in his opinion "it is the hottest curry ever. When Virgin Media approached me, I saw it as a challenge."
The 'brain storming' dish has been created by executive chef Vivek Singh of London's Chinnamon Club restaurant, for a contest that marks the launch of Virgin Media's Bollywood Movies on Demand service.
The dish containing the Dorset Naga, a chilli that is 100 times hotter than a regular jalapeno as well as lamb and other peppers, is so hot that it comes with a health warning. Diners are required to sign a disclaimer saying they are aware of the nature and risks involved in tasting the curry before eating it.
Toby Steele, 19, a student from Brighton, was the first to taste the dish at the restaurant on Great Smith Street in Westminster.
"I'm usually a korma man and I suspect this is the hottest thing I've ever tasted. It was nice actually, you could really taste the spices. The initial taste wasn't that hot but a couple of minutes later, I felt a bit floaty and light-headed," he said. Vivek Singh said that in his opinion "it is the hottest curry ever. When Virgin Media approached me, I saw it as a challenge."
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